The Stars and Stripes will trade tackles with Wales in Group B on Monday, November 21 at the Al Rayyan Stadium at 19:00 GMT.
This game could be one of the most entertaining at the World Cup this year. Both teams are returning to the World Cup, but Wales would appear to be strangers having not represented in 64 years. The United States, on the other hand, are back after missing the last edition in Russia.
Both teams have not been in the best of form since securing qualification and would be seeking to get back on track.
FORM GUIDE (LAST FIVE MATCHES)
USA have been defeated once in their last five games while Wales have struggled to avoid defeat in their last five.
USA
September 27, 22 Saudi Arabia 0–0 United States Friendly
September 23, 22 Japan 2–0 United States Friendly
June 14, 22 El Salvador 1–1 United States Nations League GS
June 10, 22 United States 5–0 Grenada Nations League GS
June 5, 22 United States 0–0 Uruguay Friendly
WALES
25 September 2022 Wales 0–1 Poland Nations League A
22 September 2022 Belgium 2–1 Wales Nations League A
14 June 2022 Netherlands 3–2 Wales Nations League A
11 June 2022 Wales 1–1 Belgium Nations League A
8 June 2022 Wales 1–2 Netherlands Nations League A
HEAD TO HEAD
The two sides have clashed twice, with the United States having the greater positive share of the numbers.
26 May 2003 USA v Wales 2-0 International Friendly
12 Nov 2020 Wales v USA 0-0 International Friendly
TEAM NEWS AND PREDICTED LINE-UP
USA
USA coach Gregg Berhalter would most likely depend on the dexterous feet of Christian Pulisic and Gio Reyna while depending on the skillset of Yunus Musah and McKennie in the middle.
PREDICTED LINE-UP
(4-3-3) Turner; Dest, Long, Zimmerman, Robinson; McKennie, Adams, Yunus; Pulisic, Ferreira, Reyna
WALES
The Dragons may not be entirely sorted with quality to the extreme. However, the excellence of Gareth Bale coupled with the availability of Brennan Johnson could present manager Rob Page with an opportunity to shock the world.
PREDICTED LINE-UP
(3-4-2-1) Hennessey; Norrington-Davies, Rodon, Ampadu; C Roberts, Allen, Ramsey, N Williams; Johnson; Bale; Moore