In a vetting which was heavily witnessed by scores of party supporters , Mr Ayesu was lifted shoulder-high after what many described as an incredible performance.
But after the euphoria that surrounded his vetting, the Vetting Committee on Tuesday afternoon indicated that Mr Ayesu is unfit to contest in the primaries.
According to Committee, Mr Ayesu has not lived in the Sunyani West Constituency for the required number of years and therefore he cannot participate in the party's upcoming primaries.
In a related development, another contender, Evelyn Akantoa was also deemed as disqualified, following concerns about her membership of the constituency in addition to others allegations of falsifed documents.
Her supporters have therefore vowed to employ all means to ensure that she gets back into the race.
Meanwhile, Chairman of the Vetting Committee and Deputy National General Secretary of the NDC, Mustapha Foyoo Gbande says neither Ayesu nor Evelyn Akantoa have been disqualified.
Speaking in an interview with MyJoyOnline on the back of the tensions of the constituency, he explained that there is no substantive decision on Mr Ernest Ayesu and Evelyn Akantoah.
According to him, the candidates have temporarily been placed on hold awaiting a final determination of the issues surrounding their candidature.
Mr Gbande said the outstanding issues which came up in the course of the vetting will be addressed by the close of day, Tuesday.