Southampton head coach Ralph Hassenhutl handed the young defender his first start since he joined them last summer from Spanish La Liga side Real Valladolid.
Salisu played 90-minutes in a four man defence with Jan Bednarek in central defence and Ryan Betrand and Walker-Peters as the laterals.
The 21-year old helped the Saints record their first win and first clean sheet in five games.
The 2-0 win qualified Southampton to the quarter finals of the English FA Cup and will play AFC Bournemouth.
By Francis Hema|3news.com|Ghana]]>