Asante Kotoko, the reigning champions of the Ghana Premier League, will face a tough challenge in the last 16 of the 2022/2023 FA Cup.
They have been drawn against current league leaders Aduana Stars and will travel to Nana Agyemang Badu Park for the match.
Asante Kotoko have only won once in their previous ten meetings against Aduana Stars in Dormaa.
In other fixtures, Real Tamale United will lock horns with Samartex at the Aliu Mahama Stadium while Steadfast United visit King Faisal. Another Premier League side Nsoatreman FC will also host Debibi United in the Northern Zone.
Dreams FC will look to build on their round-of-32 victory over Hearts of Oak when they host Division One side Liberty Professionals at Dawu Park.
Volta Rangers are paired with Legon Cities while their regional rivals, Hearts of Lions will trade tackles with Skyy FC.
Ebusua Dwarfs will also come up against Kotoku Royals who have struggled all season in the Ghana Premier League.
The fixtures have been scheduled to take place from February 24th to February 26th, 2023.